Bells HardingstoneThe Midwest is home to some of the most tranquil and rejuvenating spa & wellness resorts in the United States. These destinations offer more than just massages and facials; they provide holistic healing experiences surrounded by nature, comfort, and luxury. From lakeside sanctuaries to mountain retreats, each resort blends serenity with elegance to create unforgettable wellness experiences. Whether you seek physical renewal, emotional balance, or mental peace, the top spa & wellness resorts in Midwest promise the perfect escape for relaxation and restoration.
Top 35 Spa and Wellness Resorts in Midwest
1. The American Club / Kohler Waters Spa – Kohler, Wisconsin
Among the most luxurious spa & wellness resorts in Midwest, The American Club offers hydrotherapy, thermal pools, and holistic wellness experiences. Guests enjoy the renowned Kohler Waters Spa treatments that use innovative water techniques to restore balance. With fine dining, golf, and serene accommodation, it’s a complete rejuvenation destination. Its tranquil setting and world-class service make it a top choice for anyone seeking relaxation and renewal in the Midwest.
2. Sundara Inn & Spa – Wisconsin Dells, Wisconsin
Sundara Inn & Spa stands out as one of the premier spa & wellness resorts in Midwest, offering adults-only serenity surrounded by pine forests. It features sacred hot pools, purifying baths, and healing massages focused on mindfulness and self-care. The resort encourages digital detox, making it ideal for guests seeking peace and reconnection. Its holistic approach to rejuvenation and tranquil atmosphere make it a leading destination for ultimate relaxation.
3. WELL Spa + Salon at Grand Geneva Resort & Spa – Lake Geneva, Wisconsin
This resort blends luxurious accommodations with a world-class spa experience, making it one of the top spa & wellness resorts in Midwest. WELL Spa offers personalized massages, facials, and full-body rituals that combine nature-inspired therapies with modern wellness science. Its scenic location, professional staff, and variety of treatment options make it perfect for travelers looking for both leisure and wellness in a refined environment.
4. Aspira Spa at The Osthoff Resort – Elkhart Lake, Wisconsin
Aspira Spa is renowned among spa & wellness resorts in Midwest for its peaceful lakeside setting and holistic treatments. Guests can indulge in massages, facials, and energy therapies inspired by ancient healing traditions. The resort’s calm environment and focus on organic ingredients enhance every experience. Surrounded by nature, it promotes balance, relaxation, and deep spiritual renewal, making it a perfect escape from urban stress.
5. Wild Rice Retreat – Bayfield, Wisconsin
Wild Rice Retreat offers a unique wellness experience among spa & wellness resorts in Midwest by integrating art, nature, and healing practices. Guests enjoy yoga sessions, nourishing meals, and guided creative workshops overlooking Lake Superior. Its sustainable architecture and focus on mindfulness make it a haven for creative rejuvenation. The combination of scenic beauty and holistic wellness makes it a top retreat for relaxation seekers.
6. Eagle Ridge Resort & Spa – Galena, Illinois
As one of the finest spa & wellness resorts in Midwest, Eagle Ridge Resort provides an elegant spa experience complemented by beautiful countryside views. Stonedrift Spa offers body wraps, hydrafacials, and salt therapy rooms for complete rejuvenation. The peaceful environment encourages relaxation while the resort’s luxurious amenities ensure comfort. Its balance of nature and modern wellness makes it a favorite for weekend getaways.
7. Blue Harbor Resort & Spa – Sheboygan, Wisconsin
Blue Harbor Resort & Spa is a family-friendly yet relaxing destination among spa & wellness resorts in Midwest. Overlooking Lake Michigan, it features rejuvenating spa treatments, hydrotherapy, and aromatherapy options. Guests can unwind in spacious suites, enjoy fine dining, and explore the waterfront. The blend of leisure and health-focused services makes it a great destination for couples and families seeking both recreation and renewal.
8. The Elms Hotel & Spa – Excelsior Springs, Missouri
The Elms Hotel & Spa is one of the oldest and most distinguished spa & wellness resorts in Midwest. Known for its mineral springs and therapeutic baths, it provides natural healing experiences within a historic ambiance. Modern spa services blend with heritage charm, offering massages, facials, and body treatments. The resort’s restorative atmosphere and luxurious amenities make it an enduring wellness destination.
9. Eaglewood Resort & Spa – Itasca, Illinois
Eaglewood Resort & Spa combines urban convenience with serene relaxation, ranking it among top spa & wellness resorts in Midwest. It offers comprehensive spa therapies, an indoor pool, steam rooms, and yoga facilities. The resort caters to both leisure and business travelers seeking a peaceful escape. Its proximity to Chicago makes it an accessible yet calming getaway for rejuvenation and renewal.
10. Lied Lodge at Arbor Day Farm – Nebraska City, Nebraska
Lied Lodge is nature-inspired and stands out among spa & wellness resorts in Midwest for its eco-friendly approach. Surrounded by forests, it offers soothing spa treatments and organic body therapies that promote holistic well-being. Guests can hike, meditate, and relax in a calming, natural environment. The connection to the Arbor Day Foundation enhances its focus on sustainability and environmental mindfulness.
11. Grand Hotel & Spa – Mackinac Island, Michigan
The Grand Hotel & Spa blends historic charm with modern wellness amenities, earning its place among the leading spa & wellness resorts in Midwest. Guests can enjoy island-inspired treatments, aromatherapy, and massage therapies while overlooking Lake Huron. Its elegant ambiance, scenic views, and personalized care create a rejuvenating escape that celebrates both relaxation and tradition.
12. The Spa at Four Seasons Hotel St. Louis – St. Louis, Missouri
This luxury destination is one of the top urban spa & wellness resorts in Midwest. The spa offers advanced skin therapies, body scrubs, and hydrotherapy in a serene environment overlooking the Mississippi River. The combination of five-star service, professional therapists, and modern wellness innovations creates an unmatched relaxation experience in the heart of the Midwest.
13. French Lick Resort & Spa – French Lick, Indiana
French Lick Resort is a historic retreat known for its therapeutic mineral springs, making it a top spa & wellness resort in Midwest. The spa features mineral bath therapies, massages, and body scrubs designed for full rejuvenation. Guests also enjoy elegant rooms, fine dining, and a peaceful natural setting. Its unique blend of history and healing makes it a popular wellness destination.
14. Boyne Mountain Resort & Solace Spa – Boyne Falls, Michigan
Solace Spa at Boyne Mountain Resort is among the premier spa & wellness resorts in Midwest, offering a full range of wellness treatments within a scenic mountain setting. Guests experience hydrotherapy pools, relaxation lounges, and hot stone massages. Its focus on both adventure and serenity creates a perfect balance for travelers seeking total renewal.
15. Big Cedar Lodge – Ridgedale, Missouri
Big Cedar Lodge stands among the best spa & wellness resorts in Midwest for its rustic luxury and natural beauty. The Cedar Creek Spa features stone grotto pools, fire-lit lounges, and organic treatments. Surrounded by the Ozark Mountains, the resort provides peace, relaxation, and outdoor recreation. Its commitment to holistic health and nature-inspired design makes it a top destination for wellness enthusiasts.
16. The Abbey Resort and Avani Spa – Fontana, Wisconsin
The Abbey Resort and Avani Spa is one of the most admired spa & wellness resorts in Midwest, offering lakeside serenity and rejuvenating treatments. Avani Spa specializes in personalized massages, facials, and hydrotherapy, complemented by access to saunas and whirlpools. Its peaceful Lake Geneva location, relaxing amenities, and attentive service create the perfect atmosphere for renewal and tranquility. Guests appreciate the soothing ambiance and breathtaking waterfront views.
17. The Spa at Hotel Blackhawk – Davenport, Iowa
Hotel Blackhawk’s spa combines elegance and relaxation, ranking it among the finest spa & wellness resorts in Midwest. It offers body wraps, aromatherapy, and therapeutic massages within a luxurious setting. The spa’s focus on mental relaxation and physical renewal makes it ideal for both locals and travelers. Its modern design and professional therapists ensure a superior wellness experience for guests seeking inner balance.
18. The Spa at Cedarhurst – Cedarhurst, Missouri
A hidden gem among spa & wellness resorts in Midwest, The Spa at Cedarhurst is known for personalized care and holistic healing. Guests enjoy full-body massages, facials, and rejuvenating mud wraps that restore vitality. Surrounded by calm nature, it promotes mindfulness and self-care. The spa’s intimate environment and warm hospitality make it a peaceful escape from city life.
19. Inn at Bay Harbor and Spa – Bay Harbor, Michigan
This coastal-style resort is one of the top spa & wellness resorts in Midwest, offering stunning Lake Michigan views and luxurious spa treatments. The Spa at Bay Harbor provides facials, massages, and body therapies designed for total renewal. Guests can enjoy nearby golf, fine dining, and lakeside relaxation. Its elegant setting and dedication to wellness make it a standout destination for rejuvenation.
20. The Spa at Chateau on the Lake – Branson, Missouri
Chateau on the Lake offers an enchanting spa experience among spa & wellness resorts in Midwest. Guests can unwind with massages, hydrotherapy, and aromatherapy treatments overlooking Table Rock Lake. The serene mountain backdrop enhances the relaxation experience. With its combination of nature, comfort, and wellness programs, it provides a peaceful haven for those seeking to recharge.
21. The Spa at The Pfister Hotel – Milwaukee, Wisconsin
Located in a historic landmark, The Pfister Spa is a sophisticated destination among spa & wellness resorts in Midwest. It features massage therapies, facials, and body treatments infused with natural ingredients. The spa’s elegant design, tranquil music, and professional service make it a sanctuary for self-care. Its balance of old-world charm and modern luxury attracts wellness enthusiasts from across the region.
22. Spa Shiki at The Lodge of Four Seasons – Lake Ozark, Missouri
Spa Shiki is one of the most recognized spa & wellness resorts in Midwest for its Japanese-inspired therapies. Treatments include shiatsu massage, detoxifying wraps, and reflexology. The tranquil lakeside environment promotes deep relaxation and mindfulness. Its fusion of Eastern techniques and Western comfort makes it a top choice for visitors seeking harmony of body and mind.
23. The Spa at The Edgewater – Madison, Wisconsin
The Edgewater Spa offers lakeside tranquility and luxurious pampering, ranking it high among spa & wellness resorts in Midwest. Guests enjoy massages, facial treatments, and body therapies using organic products. Overlooking Lake Mendota, the spa provides a calm and modern retreat. Its commitment to relaxation and refined atmosphere make it an ideal destination for both leisure and business travelers.
24. Grand Traverse Resort and Spa – Traverse City, Michigan
Grand Traverse Resort and Spa stands out among spa & wellness resorts in Midwest for its variety of treatments and expansive facilities. The spa offers body scrubs, hydrafacials, and relaxation rooms designed for complete rejuvenation. With scenic surroundings and access to golf, beaches, and fine dining, it provides a well-rounded wellness experience for guests of all ages.
25. The Spa at West Baden Springs Hotel – West Baden Springs, Indiana
This historic spa is one of the most iconic spa & wellness resorts in Midwest. Surrounded by domed architecture and lush gardens, the spa features mineral baths, massages, and skin therapies rooted in traditional healing. Guests are transported to a world of timeless luxury and calm. The combination of grandeur and wellness creates a truly rejuvenating experience.
26. The Spa at Resort at Port Ludington – Ludington, Michigan
Among the scenic spa & wellness resorts in Midwest, this lakeside destination offers a peaceful environment for rest and renewal. Guests enjoy aromatherapy massages, facials, and nature-inspired treatments using organic ingredients. The serene lake views, professional therapists, and calming energy make it a relaxing haven for those seeking balance and inner peace.
27. The Spa at The Inn on Woodlake – Kohler, Wisconsin
Located near Kohler Waters Spa, this boutique retreat ranks among top spa & wellness resorts in Midwest. It offers massages, facials, and access to meditation lounges for deep relaxation. Guests appreciate the peaceful lakefront setting and modern amenities. Its focus on tranquility and simplicity makes it ideal for guests seeking privacy and restorative wellness.
28. The Spa at Chetola Resort – Blowing Rock, Missouri
Known for its rustic charm and healing atmosphere, Chetola Resort is one of the coziest spa & wellness resorts in Midwest. The spa offers massages, skincare treatments, and wellness programs aimed at stress relief. Its mountain-inspired setting enhances the feeling of serenity. Guests leave refreshed and reconnected to nature through mindful treatments and personalized care.
29. The Spa at Amway Grand Plaza – Grand Rapids, Michigan
The Amway Grand Plaza’s spa is a luxurious urban oasis among spa & wellness resorts in Midwest. It offers a blend of European-inspired therapies, including facials, massages, and body rituals. The elegant setting and professional service create a refined wellness escape. Perfect for business travelers and couples, it combines sophistication with complete relaxation.
30. The Spa at The Lodge at Geneva-on-the-Lake – Geneva, Ohio
This lakefront destination is one of the most relaxing spa & wellness resorts in Midwest. Guests enjoy massages, wraps, and facials while overlooking the beautiful Lake Erie. Its peaceful location, attentive staff, and rejuvenating treatments make it an ideal spot for wellness seekers. The combination of natural surroundings and holistic care ensures deep relaxation.
31. The Spa at The Delafield Hotel – Delafield, Wisconsin
The Delafield Hotel Spa ranks among elegant spa & wellness resorts in Midwest with its boutique charm and luxury treatments. Guests can enjoy massages, skincare, and aromatherapy designed to promote full relaxation. Its cozy atmosphere and personalized approach create a truly intimate wellness experience. The combination of sophistication and comfort makes it a favorite for weekend retreats.
32. The Spa at The Prairie Club – Valentine, Nebraska
The Prairie Club offers a peaceful escape among spa & wellness resorts in Midwest, surrounded by rolling plains and open skies. Guests can unwind with nature-inspired massages, facials, and detox therapies. The serene landscape enhances every treatment, encouraging reflection and renewal. Its simplicity and connection to nature provide a unique sense of grounding and calm.
33. The Spa at Mission Point Resort – Mackinac Island, Michigan
Mission Point Resort’s spa is one of the most scenic spa & wellness resorts in Midwest. Overlooking Lake Huron, it offers body treatments, facials, and aromatherapy inspired by island tranquility. Guests can unwind in private lounges and enjoy the fresh lake air. Its charming island setting and relaxing spa experiences make it an unforgettable retreat.
34. The Spa at Arrowwood Resort – Alexandria, Minnesota
Arrowwood Resort offers one of the most family-friendly spa & wellness resorts in Midwest. The Darling Reflections Spa provides massages, skincare, and body treatments aimed at total relaxation. Its lakeside views, warm staff, and cozy environment make it a welcoming destination for visitors seeking peace and rejuvenation. Guests enjoy both leisure and wellness in harmony.
35. The Spa at The Grand View Lodge – Nisswa, Minnesota
Grand View Lodge’s Glacial Waters Spa is a leading destination among spa & wellness resorts in Midwest. Treatments use mineral-rich ingredients inspired by local glacial waters. Guests can experience massages, facials, and wellness rituals in a natural, soothing atmosphere. Surrounded by lakes and forests, it offers an authentic connection to nature that enhances relaxation and well-being.
Reasons Why They Are The Top Spa and Wellness Resorts in Midwest
- Exceptional holistic treatments that focus on both physical and mental well-being.
- Breathtaking natural settings including lakes, forests, and mountain views that enhance relaxation.
- Highly trained therapists and wellness experts delivering personalized care.
- Luxurious amenities such as hydrotherapy pools, saunas, meditation rooms, and yoga studios.
- A combination of modern wellness techniques and traditional healing methods.
- Organic and locally sourced spa products promoting sustainability and skin health.
- Elegant accommodations that offer peace and comfort alongside spa facilities.
- Outstanding customer service that ensures every guest enjoys a transformative wellness experience.
Reasons Why You Should Visit These Top Spa and Wellness Resorts in Midwest
- To escape daily stress and recharge your body and mind in a serene environment.
- To enjoy world-class spa treatments designed for relaxation, beauty, and health.
- To experience natural healing through mineral springs, hydrotherapy, and nature walks
- To reconnect with nature in scenic destinations surrounded by lakes, woods, and mountains.
- To celebrate special occasions like anniversaries or honeymoons in a peaceful setting.
- To access professional wellness programs that promote long-term health and happiness.
- To indulge in a luxurious getaway that blends comfort, care, and rejuvenation.
Conclusion
The top spa & wellness resorts in Midwest offer an unmatched blend of luxury, nature, and holistic care. Each resort provides a sanctuary for guests to escape, heal, and rediscover themselves. From the serene waters of Wisconsin to the rolling hills of Missouri and Michigan’s tranquil shores, these destinations embody true wellness and relaxation. Whether for a weekend retreat or an extended vacation, visiting these top spa & wellness resorts in Midwest guarantees a transformative experience that nurtures the body, calms the mind, and renews the spirit.